› 3c9c

X-ray diffraction
3.2Å resolution

Structural Basis of Histone H4 Recognition by p55

Released:
DOI: 10.2210/pdb3c9c/pdb
PDB entry 3c9c coloured by chain, front view.
PDB entry 3c9c coloured by chain, side view.
PDB entry 3c9c coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Structural basis of histone H4 recognition by p55.
Song JJ, Garlick JD, Kingston RE
Genes Dev 22 1313-8 (2008)
PMID: 18443147

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160787 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Chromatin assembly factor 1 p55 subunit Chain: A
Molecule details ›
Chain: A
Length: 432 amino acids
Theoretical weight: 48.82 KDa
Source organism: Drosophila melanogaster
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q24572 (Residues: 1-430; Coverage: 100%)
Gene names: CG4236, Caf1, Caf1-55
Sequence domains:
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase
Histone H4 Chain: B
Molecule details ›
Chain: B
Length: 27 amino acids
Theoretical weight: 3.19 KDa
Source organism: Drosophila melanogaster
Expression system: Not provided
UniProt:
  • Canonical: P84040 (Residues: 16-42; Coverage: 26%)
Gene names: CG31611, CG3379, CG33869, CG33871, CG33873, CG33875, CG33877, CG33879, CG33881, CG33883, CG33885, CG33887, CG33889, CG33891, CG33893, CG33895, CG33897, CG33899, CG33901, CG33903, CG33905, CG33907, CG33909, H4, H4r, His4, His4:CG31611, His4:CG33869, His4:CG33871, His4:CG33873, His4:CG33875, His4:CG33877, His4:CG33879, His4:CG33881, His4:CG33883, His4:CG33885, His4:CG33887, His4:CG33889, His4:CG33891, His4:CG33893, His4:CG33895, His4:CG33897, His4:CG33899, His4:CG33901, His4:CG33903, His4:CG33905, His4:CG33907, His4:CG33909, His4r

Ligands and Environments

1 bound ligand:
Ligand CD 7 x CD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12B
Spacegroup: P3121
Unit cell:
a: 150.119Å b: 150.119Å c: 97.821Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.203 0.203 0.242
Expression systems:
  • Spodoptera frugiperda
  • Not provided

Quick links

Citations

37 review citations

The Polycomb complex PRC2 and its mark in life.
Margueron et al. (2011)
36 more

6 mentions without citation

Histone chaperone networks shaping chromatin function.
Hammond et al. (2017)
5 more