› 3cf3

X-ray diffraction
4.25Å resolution

Structure of P97/vcp in complex with ADP

Released:
DOI: 10.2210/pdb3cf3/pdb
PDB entry 3cf3 coloured by chain, front view.
PDB entry 3cf3 coloured by chain, side view.
PDB entry 3cf3 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Improved structures of full-length p97, an AAA ATPase: implications for mechanisms of nucleotide-dependent conformational change.
Davies JM, Brunger AT, Weis WI
Structure 16 715-26 (2008)
PMID: 18462676

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169640 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transitional endoplasmic reticulum ATPase Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 806 amino acids
Theoretical weight: 89.44 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q01853 (Residues: 1-806; Coverage: 100%)
Gene name: Vcp
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand ADP 6 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: I222
Unit cell:
a: 163.97Å b: 178.93Å c: 320.64Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.198 0.226
Expression system: Escherichia coli

Quick links

Citations

37 review citations

The role of bacterial enhancer binding proteins as specialized activators of σ54-dependent transcription.
Bush et al. (2012)
36 more

35 mentions without citation

Structure and function of the AAA+ ATPase p97/Cdc48p.
Xia et al. (2016)
34 more