› 3cmp

X-ray diffraction
2.8Å resolution

Crystal structure of Siderocalin (NGAL, Lipocalin 2) K125A mutant complexed with Ferric Enterobactin

Released:
DOI: 10.2210/pdb3cmp/pdb
PDB entry 3cmp coloured by chain, front view.
PDB entry 3cmp coloured by chain, side view.
PDB entry 3cmp coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Clifton MC, Strong RK

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160356 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neutrophil gelatinase-associated lipocalin Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 198 amino acids
Theoretical weight: 22.54 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P80188 (Residues: 1-198; Coverage: 100%)
Gene names: HNL, LCN2, NGAL
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

6 bound ligands:
Ligand FE 3 x FE
Ligand NA 7 x NA
Ligand SO4 3 x SO4
Ligand EB4 2 x EB4
Ligand GOL 3 x GOL
Ligand DBH 2 x DBH
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: P41212
Unit cell:
a: 114.908Å b: 114.908Å c: 118.832Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.251 0.248 0.304
Expression system: Escherichia coli

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