› 3d3k

X-ray diffraction
2.2Å resolution

Crystal structure of human Edc3p

Released:
DOI: 10.2210/pdb3d3k/pdb
PDB entry 3d3k coloured by chain, front view.
PDB entry 3d3k coloured by chain, side view.
PDB entry 3d3k coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of human Edc3 and its functional implications.
Ling SH, Decker CJ, Walsh MA, She M, Parker R, Song H
Mol Cell Biol 28 5965-76 (2008)
PMID: 18678652

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Enhancer of mRNA-decapping protein 3 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 259 amino acids
Theoretical weight: 28.59 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96F86 (Residues: 250-508; Coverage: 51%)
Gene names: EDC3, LSM16, PP844, YJDC, YJEFN2
Sequence domains:
Structure domains: YjeF N-terminal domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: C2221
Unit cell:
a: 94.377Å b: 169.204Å c: 163.609Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.229 0.228 0.256
Expression system: Escherichia coli

Quick links

Citations

17 review citations

P-bodies and stress granules: possible roles in the control of translation and mRNA degradation.
Decker et al. (2012)
16 more

5 mentions without citation

The role of disordered protein regions in the assembly of decapping complexes and RNP granules.
Jonas et al. (2013)
4 more