Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
Interleukin-23 complex and IG-heavy chain (preferred)
PDBe Complex ID:
PDB-CPX-208619 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Immunoglobulin heavy constant gamma 1
Molecule details ›
Chain: B
Length: 223 amino acids
Theoretical weight: 23.84 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Length: 223 amino acids
Theoretical weight: 23.84 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P01857 (Residues: 1-108; Coverage: 27%)
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Interleukin-23 subunit alpha
Molecule details ›
Chain: C
Length: 178 amino acids
Theoretical weight: 19.67 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: Interleukin 23 subunit alpha
Structure domains: Growth Hormone; Chain: A;
Length: 178 amino acids
Theoretical weight: 19.67 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical: Q9NPF7 (Residues: 20-189; Coverage: 100%)
Sequence domains: Interleukin 23 subunit alpha
Structure domains: Growth Hormone; Chain: A;
Interleukin-12 subunit beta
Molecule details ›
Chain: D
Length: 306 amino acids
Theoretical weight: 34.75 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: Cytokine interleukin-12p40 C-terminus
Structure domains: Immunoglobulins
Length: 306 amino acids
Theoretical weight: 34.75 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical: P29460 (Residues: 23-328; Coverage: 100%)
Sequence domains: Cytokine interleukin-12p40 C-terminus
Structure domains: Immunoglobulins
