› 3d95

X-ray diffraction
1.2Å resolution

Crystal Structure of the R132K:Y134F:R111L:L121E:T54V Mutant of Apo-Cellular Retinoic Acid Binding Protein Type II at 1.20 Angstroms Resolution

Released:
DOI: 10.2210/pdb3d95/pdb
PDB entry 3d95 coloured by chain, front view.
PDB entry 3d95 coloured by chain, side view.
PDB entry 3d95 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural analysis of site-directed mutants of cellular retinoic acid-binding protein II addresses the relationship between structural integrity and ligand binding.
Vaezeslami S, Jia X, Vasileiou C, Borhan B, Geiger JH
Acta Crystallogr D Biol Crystallogr 64 1228-39 (2008)
PMID: 19018099

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151430 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cellular retinoic acid-binding protein 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 137 amino acids
Theoretical weight: 15.51 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P29373 (Residues: 2-138; Coverage: 99%)
Gene name: CRABP2
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 32-ID
Spacegroup: P1
Unit cell:
a: 34.591Å b: 36.897Å c: 57.811Å
α: 73.28° β: 75.91° γ: 87.76°
R-values:
R R work R free
0.141 0.138 0.176
Expression system: Escherichia coli

Quick links

Citations

8 citation in other articles

Retinoic acid receptors: from molecular mechanisms to cancer therapy.
di Masi et al. (2015)
7 more

3 mentions without citation

Structural analysis of site-directed mutants of cellular retinoic acid-binding protein II addresses the relationship between structural integrity and ligand binding.
Vaezeslami et al. (2008)
2 more