3dvk

X-ray diffraction
2.3Å resolution

Crystal Structure of Ca2+/CaM-CaV2.3 IQ domain complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-143943 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Calmodulin-1 Chain: A
Molecule details ›
Chain: A
Length: 148 amino acids
Theoretical weight: 16.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DP23 (Residues: 2-149; Coverage: 99%)
Gene names: CALM, CALM1, CAM, CAM1
Sequence domains: EF-hand domain pair
Structure domains: EF-hand
Voltage-dependent R-type calcium channel subunit alpha-1E Chain: B
Molecule details ›
Chain: B
Length: 23 amino acids
Theoretical weight: 2.73 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q07652 (Residues: 1818-1837; Coverage: 1%)
Gene names: Cach6, Cacna1e, Cacnl1a6

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P6122
Unit cell:
a: 44.262Å b: 44.262Å c: 337.941Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.258 0.256 0.291
Expression system: Escherichia coli