3e0g

X-ray diffraction
3.1Å resolution

Structure of the Leukemia Inhibitory Factor Receptor (LIF-R) domains D1-D5

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-154857 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (4 distinct):
Leukemia inhibitory factor receptor Chain: A
Molecule details ›
Chain: A
Length: 483 amino acids
Theoretical weight: 54.91 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P42702 (Residues: 52-534; Coverage: 46%)
Gene name: LIFR
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, MAN, FUC
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, FUC
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: C2
Unit cell:
a: 90.008Å b: 143.169Å c: 80.362Å
α: 90° β: 110.38° γ: 90°
R-values:
R R work R free
0.255 0.252 0.309
Expression system: Spodoptera frugiperda