Function and Biology Details
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
DNA polymerase delta (preferred)
PDBe Complex ID:
PDB-CPX-155824 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
DNA polymerase delta subunit 2
Molecule details ›
Chains: A, C, E, G
Length: 476 amino acids
Theoretical weight: 52.22 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Sequence domains:
Structure domains:
Length: 476 amino acids
Theoretical weight: 52.22 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical:
P49005 (Residues: 1-469; Coverage: 100%)
Sequence domains:
Structure domains:
DNA polymerase delta subunit 3
Molecule details ›
Chains: B, D, F, H
Length: 144 amino acids
Theoretical weight: 16.23 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Structure domains: DNA polymerase delta, p66 (Cdc27) subunit, wHTH domain
Length: 144 amino acids
Theoretical weight: 16.23 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: Q15054 (Residues: 1-144; Coverage: 31%)
Structure domains: DNA polymerase delta, p66 (Cdc27) subunit, wHTH domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
RIGAKU FR-E SUPERBRIGHT
Spacegroup:
P21
Expression system: Not provided
