› 3eh9

X-ray diffraction
1.7Å resolution

Crystal structure of death associated protein kinase complexed with ADP

Released:
DOI: 10.2210/pdb3eh9/pdb
PDB entry 3eh9 coloured by chain, front view.
PDB entry 3eh9 coloured by chain, side view.
PDB entry 3eh9 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural insight into nucleotide recognition by human death-associated protein kinase.
McNamara LK, Watterson DM, Brunzelle JS
Acta Crystallogr D Biol Crystallogr 65 241-8 (2009)
PMID: 19237746

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156788 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Death-associated protein kinase 1 Chain: A
Molecule details ›
Chain: A
Length: 294 amino acids
Theoretical weight: 33.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P53355 (Residues: 2-285; Coverage: 20%)
Gene names: DAPK, DAPK1
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand ADP 1 x ADP
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: P212121
Unit cell:
a: 46.862Å b: 62.675Å c: 88.23Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.178 0.217
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Death Associated Protein Kinase 1 (DAPK1): A Regulator of Apoptosis and Autophagy.
Singh et al. (2016)
6 other articles

2 mentions without citation

Structural insight into nucleotide recognition by human death-associated protein kinase.
McNamara et al. (2009)
1 more