› 3ehr

X-ray diffraction
1.95Å resolution

Crystal Structure of Human Osteoclast Stimulating Factor

Released:
DOI: 10.2210/pdb3ehr/pdb
PDB entry 3ehr coloured by chain, front view.
PDB entry 3ehr coloured by chain, side view.
PDB entry 3ehr coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of human osteoclast stimulating factor.
Tong S, Zhou H, Gao Y, Zhu Z, Zhang X, Teng M, Niu L
Proteins 75 245-51 (2009)
PMID: 19137598

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187798 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Osteoclast-stimulating factor 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 222 amino acids
Theoretical weight: 24.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q92882 (Residues: 1-214; Coverage: 100%)
Gene name: OSTF1
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 6 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P1
Unit cell:
a: 28.306Å b: 57.935Å c: 60.477Å
α: 61.75° β: 76.53° γ: 90.08°
R-values:
R R work R free
0.181 0.178 0.239
Expression system: Escherichia coli

Quick links

Citations

3 citation in other articles

Osteoclast stimulation factor 1 (Ostf1) KNOCKOUT increases trabecular bone mass in mice.
Vermeren et al. (2017)
2 more

4 mentions without citation

The VSGB 2.0 model: a next generation energy model for high resolution protein structure modeling.
Li et al. (2011)
3 more