Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- WD40 repeat
- WD40/YVTN repeat-like-containing domain superfamily
- WD40 repeat, conserved site
- WD40-repeat-containing domain superfamily
- DNA damage-binding protein 2
- Cleavage/polyadenylation specificity factor, A subunit, C-terminal
- Quinoprotein alcohol dehydrogenase-like superfamily
- Cleavage/polyadenylation specificity factor, A subunit, N-terminal
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
UV DNA damage recognition complex DBB1-DBB2 (preferred)
PDBe Complex ID:
PDB-CPX-172478 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
DNA damage-binding protein 1
Molecule details ›
Chains: A, C, E
Length: 1158 amino acids
Theoretical weight: 129.27 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains:
Structure domains:
Length: 1158 amino acids
Theoretical weight: 129.27 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
Q16531 (Residues: 1-1140; Coverage: 100%)
Sequence domains:
Structure domains:
DNA damage-binding protein 2
Molecule details ›
Chains: B, D, F
Length: 436 amino acids
Theoretical weight: 49.05 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: WD domain, G-beta repeat
Structure domains:
Length: 436 amino acids
Theoretical weight: 49.05 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical: Q92466 (Residues: 10-427; Coverage: 98%)
Sequence domains: WD domain, G-beta repeat
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 8-BM
Spacegroup:
R32
Expression system: Trichoplusia ni
