› 3eij

X-ray diffraction
2.8Å resolution

Crystal structure of Pdcd4

Released:
DOI: 10.2210/pdb3eij/pdb
PDB entry 3eij coloured by chain, front view.
PDB entry 3eij coloured by chain, side view.
PDB entry 3eij coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis for translational inhibition by the tumour suppressor Pdcd4.
Loh PG, Yang HS, Walsh MA, Wang Q, Wang X, Cheng Z, Liu D, Song H
EMBO J 28 274-85 (2009)
PMID: 19153607

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176086 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Programmed cell death protein 4 Chains: A, B
Molecule details ›
Chains: A, B
Length: 321 amino acids
Theoretical weight: 35.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q53EL6 (Residues: 157-469; Coverage: 67%)
Gene names: H731, PDCD4
Sequence domains: MA3 domain
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P3121
Unit cell:
a: 170.325Å b: 170.325Å c: 66.919Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.235 0.235 0.277
Expression system: Escherichia coli

Quick links

Citations

25 review citations

From unwinding to clamping - the DEAD box RNA helicase family.
Linder et al. (2011)
24 more

5 mentions without citation

Structural basis for translational inhibition by the tumour suppressor Pdcd4.
Loh et al. (2009)
4 more