› 3ek9

X-ray diffraction
2.6Å resolution

SPRY Domain-containing SOCS Box Protein 2: Crystal Structure and Residues Critical for Protein Binding

Released:
DOI: 10.2210/pdb3ek9/pdb
PDB entry 3ek9 coloured by chain, front view.
PDB entry 3ek9 coloured by chain, side view.
PDB entry 3ek9 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
SPRY domain-containing SOCS box protein 2: crystal structure and residues critical for protein binding.
Kuang Z, Yao S, Xu Y, Lewis RS, Low A, Masters SL, Willson TA, Kolesnik TB, Nicholson SE, Garrett TJ, Norton RS
J Mol Biol 386 662-74 (2009)
PMID: 19154741

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131586 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SPRY domain-containing SOCS box protein 2 Chain: A
Molecule details ›
Chain: A
Length: 213 amino acids
Theoretical weight: 23.37 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: O88838 (Residues: 12-224; Coverage: 81%)
Gene names: Grcc9, Spsb2, Ssb2
Sequence domains: SPRY domain

Ligands and Environments

1 bound ligand:
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P212121
Unit cell:
a: 34.255Å b: 68.176Å c: 69.012Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.173 0.168 0.273
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Functional characterization of SAG/RBX2/ROC2/RNF7, an antioxidant protein and an E3 ubiquitin ligase.
Sun et al. (2013)
4 more

7 mentions without citation

Structure and function of the SPRY/B30.2 domain proteins involved in innate immunity.
D'Cruz et al. (2013)
6 more