3eot

X-ray diffraction
1.9Å resolution

Crystal structure of LAC031, an engineered anti-VLA1 Fab

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-213245 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
FAB FRAGMENT, HEAVY CHAIN Chain: H
Molecule details ›
Chain: H
Length: 226 amino acids
Theoretical weight: 24.22 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
Structure domains: Immunoglobulins
FAB FRAGMENT, LIGHT CHAIN Chain: L
Molecule details ›
Chain: L
Length: 215 amino acids
Theoretical weight: 23.51 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P21212
Unit cell:
a: 83.163Å b: 132.425Å c: 41.827Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.236 0.234 0.27
Expression system: Escherichia coli