Function and Biology Details
Reaction catalysed:
ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153254 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Growth/differentiation factor 5
Molecule details ›
Chain: B
Length: 117 amino acids
Theoretical weight: 13.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines
Length: 117 amino acids
Theoretical weight: 13.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P43026 (Residues: 387-501; Coverage: 24%)
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines
Bone morphogenetic protein receptor type-1B
Molecule details ›
Chain: C
Length: 119 amino acids
Theoretical weight: 13.21 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains: Activin types I and II receptor domain
Structure domains: CD59
Length: 119 amino acids
Theoretical weight: 13.21 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical: P36898 (Residues: 14-126; Coverage: 23%)
Sequence domains: Activin types I and II receptor domain
Structure domains: CD59
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SLS BEAMLINE X06SA, BESSY BEAMLINE 14.1
Spacegroup:
P42212
Expression system: Escherichia coli
