› 3f57

X-ray diffraction
2.9Å resolution

Crystal structure of human erythroid beta spectrin repeats 14 and 15 (ankyrin binding domain)

Released:
DOI: 10.2210/pdb3f57/pdb
PDB entry 3f57 coloured by chain, front view.
PDB entry 3f57 coloured by chain, side view.
PDB entry 3f57 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structures of the spectrin-ankyrin interaction binding domains.
Ipsaro JJ, Huang L, Mondragón A
Blood 113 5385-93 (2009)
PMID: 19141864

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145745 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Spectrin beta chain, erythrocytic Chains: A, B
Molecule details ›
Chains: A, B
Length: 225 amino acids
Theoretical weight: 25.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P11277 (Residues: 1686-1907; Coverage: 10%)
Gene names: SPTB, SPTB1
Sequence domains: Spectrin repeat
Structure domains: Methane Monooxygenase Hydroxylase; Chain G, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: P43212
Unit cell:
a: 65.33Å b: 65.33Å c: 288.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.265 0.262 0.322
Expression system: Escherichia coli

Quick links

Citations

12 review citations

Membrane domains based on ankyrin and spectrin associated with cell-cell interactions.
Bennett et al. (2009)
11 more

5 mentions without citation

Structures of the spectrin-ankyrin interaction binding domains.
Ipsaro et al. (2009)
4 more