Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171914 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Putative secreted protein, homologue of variola D5
Molecule details ›
Chain: A
Length: 109 amino acids
Theoretical weight: 12.37 KDa
Source organism: Ectromelia virus
Expression system: Escherichia coli
UniProt:
Sequence domains: Orthopoxvirus interleukin 18 binding protein
Structure domains: Immunoglobulins
Length: 109 amino acids
Theoretical weight: 12.37 KDa
Source organism: Ectromelia virus
Expression system: Escherichia coli
UniProt:
- Canonical:
Q85319 (Residues: 21-121; Coverage: 73%)
Sequence domains: Orthopoxvirus interleukin 18 binding protein
Structure domains: Immunoglobulins
Interleukin-18
Molecule details ›
Chain: B
Length: 158 amino acids
Theoretical weight: 18.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Interleukin-1 / 18
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)
Length: 158 amino acids
Theoretical weight: 18.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q14116 (Residues: 37-193; Coverage: 81%)
Sequence domains: Interleukin-1 / 18
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 19-ID
Spacegroup:
P212121
Expression system: Escherichia coli
