Function and Biology Details
Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Sequence domains:
- Helicase superfamily 1/2, ATP-binding domain
- P-loop containing nucleoside triphosphate hydrolase
- WD40 repeat
- DEAD/DEAH box helicase domain
- RNA helicase, DEAD-box type, Q motif
- Anaphase-promoting complex subunit 4-like, WD40 domain
- Nuclear pore complex protein
- WD40/YVTN repeat-like-containing domain superfamily
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152988 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nuclear pore complex protein Nup214
ATP-dependent RNA helicase DDX19B
Molecule details ›
Chain: B
Length: 235 amino acids
Theoretical weight: 26.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: DEAD/DEAH box helicase
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Length: 235 amino acids
Theoretical weight: 26.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
Q9UMR2 (Residues: 68-302; Coverage: 49%)
Sequence domains: DEAD/DEAH box helicase
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SLS BEAMLINE X06SA
Spacegroup:
I222
Expression system: Escherichia coli BL21
