Function and Biology Details
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145933 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cyclin-dependent kinase 4
Molecule details ›
Chains: A, C
Length: 308 amino acids
Theoretical weight: 34.18 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Protein kinase domain
Structure domains:
Length: 308 amino acids
Theoretical weight: 34.18 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P11802 (Residues: 1-303; Coverage: 100%)
Sequence domains: Protein kinase domain
Structure domains:
G1/S-specific cyclin-D3
Molecule details ›
Chains: B, D
Length: 306 amino acids
Theoretical weight: 34.06 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Structure domains: Cyclin-like
Length: 306 amino acids
Theoretical weight: 34.06 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: P30281 (Residues: 1-292; Coverage: 100%)
Sequence domains:
Structure domains: Cyclin-like
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID14-4
Spacegroup:
P42212
Expression system: Spodoptera frugiperda
