› 3g36

X-ray diffraction
1.2Å resolution

Crystal structure of the human DPY-30-like C-terminal domain

Released:
DOI: 10.2210/pdb3g36/pdb
PDB entry 3g36 coloured by chain, front view.
PDB entry 3g36 coloured by chain, side view.
PDB entry 3g36 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the C-terminal domain of human DPY-30-like protein: A component of the histone methyltransferase complex.
Wang X, Lou Z, Dong X, Yang W, Peng Y, Yin B, Gong Y, Yuan J, Zhou W, Bartlam M, Peng X, Rao Z
J Mol Biol 390 530-7 (2009)
PMID: 19481096

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189879 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein dpy-30 homolog Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 55 amino acids
Theoretical weight: 6.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9C005 (Residues: 45-99; Coverage: 56%)
Gene name: DPY30
Sequence domains: Dpy-30 motif
Structure domains: cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain

Ligands and Environments

4 bound ligands:
Ligand DTU 1 x DTU
Ligand DTT 1 x DTT
Ligand DTV 1 x DTV
Ligand HEZ 1 x HEZ
1 modified residue:
Ligand MSE 4 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-5A
Spacegroup: C2
Unit cell:
a: 83.401Å b: 51.388Å c: 51.388Å
α: 90° β: 107.58° γ: 90°
R-values:
R R work R free
0.197 0.195 0.227
Expression system: Escherichia coli

Quick links

Citations

2 review citations

The role of maintenance proteins in the preservation of epithelial cell identity during mammary gland remodeling and breast cancer initiation.
Coradini et al. (2014)
1 more

13 mentions without citation

Radial Spokes-A Snapshot of the Motility Regulation, Assembly, and Evolution of Cilia and Flagella.
Zhu et al. (2017)
12 more