› 3g5c

X-ray diffraction
2.36Å resolution

Structural and biochemical studies on the ectodomain of human ADAM22

Released:
DOI: 10.2210/pdb3g5c/pdb
PDB entry 3g5c coloured by chain, front view.
PDB entry 3g5c coloured by chain, side view.
PDB entry 3g5c coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural and biochemical studies on the ectodomain of human ADAM22
Liu H, Shim A, Chen X, He X
J. Biol. Chem. (2009)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192796 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Disintegrin and metalloproteinase domain-containing protein 22 Chains: A, B
Molecule details ›
Chains: A, B
Length: 510 amino acids
Theoretical weight: 56.25 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q9P0K1 (Residues: 233-736; Coverage: 57%)
Gene names: ADAM22, MDC2
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand NAG 6 x NAG
Ligand CA 6 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: R3
Unit cell:
a: 122.09Å b: 122.09Å c: 208.69Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.245 0.245 0.273
Expression system: Trichoplusia ni

Quick links