3g6j

X-ray diffraction
3.1Å resolution

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero tetramer (preferred)
hetero dimer
PDBe Complex ID:
PDB-CPX-208328 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Complement C3 beta chain Chains: A, C
Molecule details ›
Chains: A, C
Length: 644 amino acids
Theoretical weight: 71.32 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P01024 (Residues: 23-666; Coverage: 39%)
Gene names: C3, CPAMD1
Sequence domains:
Structure domains:
Fab light chain Chains: E, G
Molecule details ›
Chains: E, G
Length: 214 amino acids
Theoretical weight: 23.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Structure domains: Immunoglobulins
Fab heavy chain Chains: F, H
Molecule details ›
Chains: F, H
Length: 226 amino acids
Theoretical weight: 23.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: C2
Unit cell:
a: 216.436Å b: 180.417Å c: 154.584Å
α: 90° β: 115.73° γ: 90°
R-values:
R R work R free
0.218 0.214 0.282
Expression system: Escherichia coli