Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Exportin-1 and Snurportin-1 (preferred)
PDBe Complex ID:
PDB-CPX-127256 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Exportin-1
Molecule details ›
Chain: A
Length: 1071 amino acids
Theoretical weight: 123.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 1071 amino acids
Theoretical weight: 123.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
O14980 (Residues: 1-1071; Coverage: 100%)
Sequence domains:
- Importin-beta N-terminal domain
- Exportin 1-like protein
- Chromosome region maintenance or exportin repeat
- CRM1 / Exportin repeat 2
- CRM1 / Exportin repeat 3
- CRM1 C terminal
Snurportin-1
Molecule details ›
Chain: B
Length: 329 amino acids
Theoretical weight: 37.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Snurportin1
Structure domains: DNA ligase/mRNA capping enzyme
Length: 329 amino acids
Theoretical weight: 37.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: O95149 (Residues: 1-328; Coverage: 91%)
Sequence domains: Snurportin1
Structure domains: DNA ligase/mRNA capping enzyme
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 19-ID
Spacegroup:
P6422
Expression system: Escherichia coli
