Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Protein-tyrosine kinase 2-beta (preferred)
PDBe Complex ID:
PDB-CPX-171983 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein-tyrosine kinase 2-beta
Molecule details ›
Chain: A
Length: 153 amino acids
Theoretical weight: 16.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Focal adhesion targeting region
Structure domains: Nucleotidyltransferases domain 2
Length: 153 amino acids
Theoretical weight: 16.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q14289 (Residues: 861-1009; Coverage: 15%)
Sequence domains: Focal adhesion targeting region
Structure domains: Nucleotidyltransferases domain 2
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
NSLS BEAMLINE X29A
Expression system: Escherichia coli
