› 3gs3

X-ray diffraction
2.4Å resolution

Structure of the N-terminal HEAT Domain of Symplekin from D. melanogaster

Released:
DOI: 10.2210/pdb3gs3/pdb
PDB entry 3gs3 coloured by chain, front view.
PDB entry 3gs3 coloured by chain, side view.
PDB entry 3gs3 coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Crystal structure of the HEAT domain from the Pre-mRNA processing factor Symplekin.
Kennedy SA, Frazier ML, Steiniger M, Mast AM, Marzluff WF, Redinbo MR
J Mol Biol 392 115-28 (2009)
PMID: 19576221

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185332 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Symplekin Chain: A
Molecule details ›
Chain: A
Length: 257 amino acids
Theoretical weight: 28.31 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8MSU4 (Residues: 19-270; Coverage: 22%)
Gene names: CG2097, Sym
Sequence domains: Symplekin/PTA1 N-terminal
Structure domains: Leucine-rich Repeat Variant

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-BM, null
Spacegroup: P41212
Unit cell:
a: 68.336Å b: 68.336Å c: 139.34Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.207 0.265
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Recent molecular insights into canonical pre-mRNA 3'-end processing.
Sun et al. (2020)
12 other articles

5 mentions without citation

Delineating the structural blueprint of the pre-mRNA 3'-end processing machinery.
Xiang et al. (2014)
4 more