› 3gvp

X-ray diffraction
2.25Å resolution

Human SAHH-like domain of human adenosylhomocysteinase 3

Released:
DOI: 10.2210/pdb3gvp/pdb
PDB entry 3gvp coloured by chain, front view.
PDB entry 3gvp coloured by chain, side view.
PDB entry 3gvp coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Siponen MI, Wisniewska M, Arrowsmith CH, Berglund H, Bountra C, Collins R, Edwards AM, Flodin S, Flores A, Graslund S, Hammarstrom M, Johansson A, Johansson I, Karlberg T, Kotenyova T, Lehtio L, Moche M, Nordlund P, Nyman T, Persson C, Sagemark J, Schutz P, Thorsell AG, Tresaugues L, Van Den Berg S, Weigelt J, Welin M, Schueler H

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188533 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenosylhomocysteinase 3 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 435 amino acids
Theoretical weight: 48.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96HN2 (Residues: 175-607; Coverage: 71%)
Gene names: AHCYL2, KIAA0828
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand NAD 4 x NAD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P41212
Unit cell:
a: 164.188Å b: 164.188Å c: 184.614Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.182 0.226
Expression system: Escherichia coli

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