Function and Biology Details
Reaction catalysed:
The recombinant enzyme hydrolyzes proteins (serum albumin, collagen) and synthetic substrates (Z-Phe-Arg-NHMec > Z-Leu-Arg-NHMec > Z-Val-Arg-NHMec).
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Cathepsin L2 and Clitocypin-5 (preferred)
PDBe Complex ID:
PDB-CPX-130199 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cathepsin L2
Molecule details ›
Chains: A, B, C, D
Length: 221 amino acids
Theoretical weight: 24.09 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
Sequence domains: Papain family cysteine protease
Structure domains: Cysteine proteinases
Length: 221 amino acids
Theoretical weight: 24.09 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
- Canonical:
O60911 (Residues: 114-334; Coverage: 70%)
Sequence domains: Papain family cysteine protease
Structure domains: Cysteine proteinases
Clitocypin-5
Molecule details ›
Chains: E, F, G, H
Length: 152 amino acids
Theoretical weight: 16.91 KDa
Source organism: Clitocybe nebularis
Expression system: Komagataella pastoris
UniProt:
Sequence domains: Peptidase inhibitor clitocypin
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)
Length: 152 amino acids
Theoretical weight: 16.91 KDa
Source organism: Clitocybe nebularis
Expression system: Komagataella pastoris
UniProt:
- Canonical: Q3Y9I6 (Residues: 1-152; Coverage: 100%)
Sequence domains: Peptidase inhibitor clitocypin
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)
