› 3h8m

X-ray diffraction
2.1Å resolution

SAM domain of human ephrin type-a receptor 7 (EPHA7)

Released:
DOI: 10.2210/pdb3h8m/pdb
PDB entry 3h8m coloured by chain, front view.
PDB entry 3h8m coloured by chain, side view.
PDB entry 3h8m coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Walker JR, Yermekbayeva L, Butler-Cole C, Bountra C, Weigelt J, Arrowsmith CH, Edwards AM, Bochkarev A, Dhe-Paganon S, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed: 
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172269 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ephrin type-A receptor 7 Chains: A, B
Molecule details ›
Chains: A, B
Length: 90 amino acids
Theoretical weight: 10.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15375 (Residues: 919-990; Coverage: 7%)
Gene names: EHK3, EPHA7, HEK11
Sequence domains: SAM domain (Sterile alpha motif)
Structure domains: Transcription Factor, Ets-1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P21
Unit cell:
a: 40.071Å b: 54.089Å c: 40.455Å
α: 90° β: 104.84° γ: 90°
R-values:
R R work R free
0.199 0.197 0.228
Expression system: Escherichia coli

Quick links