Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149073 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ephrin type-A receptor 2
Molecule details ›
Chains: A, C, E, G, I, K, M, O
Length: 174 amino acids
Theoretical weight: 19.91 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Ephrin receptor ligand binding domain
Structure domains: Galactose-binding domain-like
Length: 174 amino acids
Theoretical weight: 19.91 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
P29317 (Residues: 28-201; Coverage: 18%)
Sequence domains: Ephrin receptor ligand binding domain
Structure domains: Galactose-binding domain-like
Ephrin-A1, secreted form
Molecule details ›
Chains: B, D, F, H, J, L, N, P
Length: 132 amino acids
Theoretical weight: 15.88 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Ephrin
Structure domains: Cupredoxins - blue copper proteins
Length: 132 amino acids
Theoretical weight: 15.88 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P20827 (Residues: 18-147; Coverage: 69%)
Sequence domains: Ephrin
Structure domains: Cupredoxins - blue copper proteins
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 24-ID-C
Spacegroup:
P1
Expression system: Homo sapiens
