Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
Growth/differentiation factor 8 and Follistatin (preferred)
PDBe Complex ID:
PDB-CPX-126655 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Growth/differentiation factor 8
Molecule details ›
Chains: A, B
Length: 109 amino acids
Theoretical weight: 12.42 KDa
Source organism: Mus musculus
Expression system: Cricetulus griseus
UniProt:
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines
Length: 109 amino acids
Theoretical weight: 12.42 KDa
Source organism: Mus musculus
Expression system: Cricetulus griseus
UniProt:
- Canonical:
O08689 (Residues: 268-376; Coverage: 31%)
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines
Follistatin
Molecule details ›
Chains: C, D
Length: 288 amino acids
Theoretical weight: 31.59 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
Sequence domains:
Length: 288 amino acids
Theoretical weight: 31.59 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
- Canonical: P19883 (Residues: 30-317; Coverage: 91%)
Sequence domains:
- Follistatin, N-terminal
- Follistatin/Osteonectin-like EGF domain
- Kazal-type serine protease inhibitor domain
