› 3hsh

X-ray diffraction
1.8Å resolution

Crystal structure of human collagen XVIII trimerization domain (Tetragonal crystal form)

Released:
DOI: 10.2210/pdb3hsh/pdb
PDB entry 3hsh coloured by chain, front view.
PDB entry 3hsh coloured by chain, side view.
PDB entry 3hsh coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of human collagen XVIII trimerization domain: A novel collagen trimerization Fold.
Boudko SP, Sasaki T, Engel J, Lerch TF, Nix J, Chapman MS, Bächinger HP
J Mol Biol 392 787-802 (2009)
PMID: 19631658

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assemblies composition:
homo trimer (preferred)
homo 24-mer
Assembly name:
PDBe Complex ID:
PDB-CPX-153816 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Collagen alpha-1(XVIII) chain Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 56 amino acids
Theoretical weight: 6.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P39060 (Residues: 1441-1496; Coverage: 3%)
Gene name: COL18A1
Sequence domains: Collagen trimerization domain
Structure domains: YefM-like fold

Ligands and Environments

2 bound ligands:
Ligand SO4 13 x SO4
Ligand GOL 9 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P4212
Unit cell:
a: 71.745Å b: 71.745Å c: 134.723Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.175 0.224
Expression system: Escherichia coli

Quick links

Citations

6 review citations

The crucial role of trimerization domains in collagen folding.
Boudko et al. (2012)
5 more

10 mentions without citation

The collagen family.
Ricard-Blum S. (2011)
9 more