› 3i3c

X-ray diffraction
2.48Å resolution

Crystal Structural of CBX5 Chromo Shadow Domain

Released:
DOI: 10.2210/pdb3i3c/pdb
PDB entry 3i3c coloured by chain, front view.
PDB entry 3i3c coloured by chain, side view.
PDB entry 3i3c coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Amaya MF, Li Z, Li Y, Kozieradzki I, Edwards AM, Arrowsmith CH, Weigelt J, Bountra C, Bochkarev A, Min J, Ouyang H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155375 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chromobox protein homolog 5 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 75 amino acids
Theoretical weight: 8.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P45973 (Residues: 110-173; Coverage: 34%)
Gene names: CBX5, HP1A
Sequence domains: Chromo shadow domain
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

1 bound ligand:
Ligand NA 2 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P21212
Unit cell:
a: 81.66Å b: 126.587Å c: 31.399Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.268 0.266 0.303
Expression system: Escherichia coli

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