› 3i8z

X-ray diffraction
1.51Å resolution

Crystal structure of human chromobox homolog 4 (CBX4)

Released:
DOI: 10.2210/pdb3i8z/pdb
PDB entry 3i8z coloured by chain, front view.
PDB entry 3i8z coloured by chain, side view.
PDB entry 3i8z coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Amaya MF, Zhihong L, Loppnau P, Kozieradzki I, Edwards AM, Arrowsmith CH, Weigelt J, Bountra C, Bochkarev A, Min J, Ouyang H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126207 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
E3 SUMO-protein ligase CBX4 Chain: A
Molecule details ›
Chain: A
Length: 55 amino acids
Theoretical weight: 6.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O00257 (Residues: 8-62; Coverage: 10%)
Gene name: CBX4
Sequence domains: Chromo (CHRromatin Organisation MOdifier) domain
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: I41
Unit cell:
a: 58.606Å b: 58.606Å c: 32.813Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.229 0.228 0.255
Expression system: Escherichia coli

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