› 3i9p

X-ray diffraction
1.9Å resolution

Crystal structure of human transthyretin - wild type

Released:
DOI: 10.2210/pdb3i9p/pdb
PDB entry 3i9p coloured by chain, front view.
PDB entry 3i9p coloured by chain, side view.
PDB entry 3i9p coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Lima LMTR, Foguel D

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
homo tetramer
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136167 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transthyretin Chains: A, B
Molecule details ›
Chains: A, B
Length: 116 amino acids
Theoretical weight: 12.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02766 (Residues: 30-145; Coverage: 91%)
Gene names: PALB, TTR
Sequence domains: HIUase/Transthyretin family
Structure domains: Transthyretin/hydroxyisourate hydrolase domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LNLS BEAMLINE D03B-MX1
Spacegroup: P21212
Unit cell:
a: 42.42Å b: 83.49Å c: 63.5Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.199 0.255
Expression system: Escherichia coli

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