› 3iin

X-ray diffraction
4.18Å resolution

Plasticity of the kink turn structural motif

Released:
DOI: 10.2210/pdb3iin/pdb
PDB entry 3iin coloured by chain, front view.
PDB entry 3iin coloured by chain, side view.
PDB entry 3iin coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Plasticity of the RNA kink turn structural motif.
Antonioli AH, Cochrane JC, Lipchock SV, Strobel SA
RNA 16 762-8 (2010)
PMID: 20145044

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113129 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
2 distinct DNA/RNA hybrid molecules
Macromolecules (4 distinct):
U1 small nuclear ribonucleoprotein A Chain: A
Molecule details ›
Chain: A
Length: 95 amino acids
Theoretical weight: 11.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P09012 (Residues: 4-98; Coverage: 34%)
Gene name: SNRPA
Sequence domains: RNA recognition motif
Group I intron Chain: B
Molecule details ›
Chain: B
Length: 197 nucleotides
Theoretical weight: 64.06 KDa
Source organism: Homo sapiens
Expression system: Not provided
DNA/RNA (5'-R(*AP*AP*GP*CP*CP*AP*CP*AP*CP*AP*GP*AP*CP*C)-D(P*AP*GP*A)-R(P*CP*GP*GP*CP*C)-3') Chain: C
Molecule details ›
Chain: C
Length: 22 nucleotides
Theoretical weight: 7.01 KDa
Source organism: Homo sapiens
Expression system: Not provided
DNA/RNA (5'-R(*CP*A)-D(P*T)-3') Chain: D
Molecule details ›
Chain: D
Length: 3 nucleotides
Theoretical weight: 894 Da
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand K 5 x K
Ligand MG 13 x MG
2 modified residues:
Ligand GTP 1 x GTP
Ligand A23 1 x A23

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X26C
Spacegroup: P4122
Unit cell:
a: 109.826Å b: 109.826Å c: 250.218Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.292 0.29 0.323
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

2 review citations

An RNA folding motif: GNRA tetraloop-receptor interactions.
Fiore et al. (2013)
1 more

3 mentions without citation

Predicting Large RNA-Like Topologies by a Knowledge-Based Clustering Approach.
Baba et al. (2016)
2 more