› 3iv1

X-ray diffraction
2.5Å resolution

Coiled-coil domain of tumor susceptibility gene 101

Released:
DOI: 10.2210/pdb3iv1/pdb
PDB entry 3iv1 coloured by chain, front view.
PDB entry 3iv1 coloured by chain, side view.
PDB entry 3iv1 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Neculai D, Avvakumov GV, Wernimont AK, Xue S, Walker JR, Li Y, Weigelt J, Bountra C, Arrowsmith CH, Edwards AM, Bochkarev A, Dhe-Paganon S, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189278 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tumor susceptibility gene 101 protein Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 78 amino acids
Theoretical weight: 9.2 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q99816 (Residues: 229-304; Coverage: 20%)
Gene name: TSG101
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces

Ligands and Environments

2 bound ligands:
Ligand SO4 1 x SO4
Ligand CL 11 x CL
1 modified residue:
Ligand MSE 24 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P3221
Unit cell:
a: 56.29Å b: 56.29Å c: 341.85Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.228 0.228 0.276
Expression system: Escherichia coli

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