3j8y

Electron Microscopy
5Å resolution

High-resolution structure of ATP analog-bound kinesin on microtubules

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-123451 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Kinesin-1 heavy chain Chain: K
Molecule details ›
Chain: K
Length: 349 amino acids
Theoretical weight: 39.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P33176 (Residues: 1-349; Coverage: 36%)
Gene names: KIF5B, KNS, KNS1
Sequence domains: Kinesin motor domain
Tubulin alpha-1B chain Chain: A
Molecule details ›
Chain: A
Length: 451 amino acids
Theoretical weight: 50.2 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: Q2XVP4 (Residues: 1-451; Coverage: 100%)
Gene name: TUBA1B
Sequence domains:
Tubulin beta chain Chain: B
Molecule details ›
Chain: B
Length: 445 amino acids
Theoretical weight: 49.98 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: F2Z5B2 (Residues: 1-420, 421-425; Coverage: 100%)
Gene name: TUBB
Sequence domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution:
Relevant EMDB volumes: EMD-6188
Expression system: Escherichia coli