3j9k

Electron Microscopy
4.1Å resolution

Structure of Dark apoptosome in complex with Dronc CARD domain

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 32-mer (preferred)
PDBe Complex ID:
PDB-CPX-181592 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Apaf-1/CED-4-related caspase activator Dapaf-1L Chains: A, C, E, G, I, K, M, O, Q, S, U, W, Y, a, c, e
Molecule details ›
Chains: A, C, E, G, I, K, M, O, Q, S, U, W, Y, a, c, e
Length: 1102 amino acids
Theoretical weight: 112.75 KDa
Source organism: Drosophila melanogaster
UniProt:
  • Canonical: Q7KLI1 (Residues: 1-583; Coverage: 41%)
Gene names: APAF-1, APAF1, ARK, Apaf, Apaf-1, Apaf1, Ark, Ark-RB, CG6829, D-Apaf-1, DARK, Dapaf-1, Dapaf-1/HAC-1, Dark, Dark/Apaf-I, Dark/Dapaf-1/HAC1, Dark/Hac-1/dApaf-1, Dark/Hac-1/dApaf1, Dmel\CG6829, Dmel_CG6829, Hac-1, Hac-1/Dark, Hac1, T1, anon-53Fa, apaf-1, apaf1, arc, ark, dAPAF-1, dApaf-1, dApaf-1/DARK/HAC-1, dApaf1, dArk, dapaf, dapaf-1, dapaf-1L, dapaf-1S, dark, dark/dapaf-1/hac-1, dark/hac-1/dapaf-1, hac-1, hac1, l(2)SH0173
Sequence domains:
Caspase Dronc Chains: B, D, F, H, J, L, N, P, R, T, V, X, Z, b, d, f
Molecule details ›
Chains: B, D, F, H, J, L, N, P, R, T, V, X, Z, b, d, f
Length: 450 amino acids
Theoretical weight: 51.21 KDa
Source organism: Drosophila melanogaster
UniProt:
  • Canonical: Q9XYF4 (Residues: 1-450; Coverage: 100%)
Gene names: CG8091, Dronc, Nc
Sequence domains: Caspase domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.1Å
Relevant EMDB volumes: EMD-2870