› 3ja9

Electron Microscopy
22Å resolution

Structure of native human PCNA

Released:
DOI: 10.2210/pdb3ja9/pdb
PDB entry 3ja9 coloured by chain, front view.
PDB entry 3ja9 coloured by chain, side view.
PDB entry 3ja9 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Molecular architecture of the Ub-PCNA/Pol η complex bound to DNA.
Lau WC, Li Y, Zhang Q, Huen MS
Sci Rep 5 15759 (2015)
PMID: 26503230
Related structures: EMD-6339

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146041 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Proliferating cell nuclear antigen Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 261 amino acids
Theoretical weight: 28.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P12004 (Residues: 1-261; Coverage: 100%)
Gene name: PCNA
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 22Å
Relevant EMDB volumes: EMD-6339
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

6 review citations

Forging Ahead through Darkness: PCNA, Still the Principal Conductor at the Replication Fork.
Choe et al. (2017)
5 more

4 mentions without citation

DNA replication: Mechanisms and therapeutic interventions for diseases.
Song et al. (2023)
3 more