Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
Interleukin-17 receptor A and Interleukin-17F (preferred)
PDBe Complex ID:
PDB-CPX-188489 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Interleukin-17F
Molecule details ›
Chains: A, B
Length: 133 amino acids
Theoretical weight: 14.92 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Interleukin-17
Structure domains: Cystine-knot cytokines
Length: 133 amino acids
Theoretical weight: 14.92 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
Q96PD4 (Residues: 31-163; Coverage: 100%)
Sequence domains: Interleukin-17
Structure domains: Cystine-knot cytokines
Interleukin-17 receptor A
Molecule details ›
Chain: C
Length: 286 amino acids
Theoretical weight: 33.22 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Structure domains:
Length: 286 amino acids
Theoretical weight: 33.22 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: Q96F46 (Residues: 32-317; Coverage: 34%)
Sequence domains:
Structure domains:
Ligands and Environments
Experiments and Validation Details
X-ray source:
SSRL BEAMLINE BL9-2, SSRL BEAMLINE BL11-1, APS BEAMLINE 23-ID-D
Spacegroup:
P41212
Expression system: Spodoptera frugiperda
