3jxt

X-ray diffraction
1.5Å resolution

Crystal structure of the third PDZ domain of SAP-102 in complex with a fluorogenic peptide-based ligand

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-131565 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Disks large homolog 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 104 amino acids
Theoretical weight: 11.15 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q62936 (Residues: 393-493; Coverage: 12%)
Gene names: Dlg3, Dlgh3
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
Voltage-dependent calcium channel gamma-2 subunit Chains: C, D
Molecule details ›
Chains: C, D
Length: 7 amino acids
Theoretical weight: 873 Da
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: O88602 (Residues: 318-323; Coverage: 2%)
Gene names: Cacng2, Stg

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X6A
Spacegroup: P212121
Unit cell:
a: 49.597Å b: 54.215Å c: 86.023Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.187 0.185 0.214
Expression systems:
  • Escherichia coli BL21
  • Not provided