› 3kd0

X-ray diffraction
1.7Å resolution

Human thioredoxin C35S,C62S,C69S,C73S mutant showing cadmium chloride bound to the active site

Released:
DOI: 10.2210/pdb3kd0/pdb
PDB entry 3kd0 coloured by chain, front view.
PDB entry 3kd0 coloured by chain, side view.
PDB entry 3kd0 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Hall G, Emsley J

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-145348 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin Chain: A
Molecule details ›
Chain: A
Length: 105 amino acids
Theoretical weight: 11.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P10599 (Residues: 1-105; Coverage: 100%)
Gene names: TRDX, TRX, TRX1, TXN
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

2 bound ligands:
Ligand CL 4 x CL
Ligand CD 1 x CD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P6122
Unit cell:
a: 53.635Å b: 53.635Å c: 154.148Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.247 0.232 0.279
Expression system: Escherichia coli

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