› 3kh0

X-ray diffraction
2.1Å resolution

Crystal structure of the Ras-association (RA) domain of RALGDS

Released:
DOI: 10.2210/pdb3kh0/pdb
PDB entry 3kh0 coloured by chain, front view.
PDB entry 3kh0 coloured by chain, side view.
PDB entry 3kh0 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Shen Y, Tempel W, Wang H, Tong Y, Guan X, Crombet L, Arrowsmith CH, Edwards AM, Bountra C, Weigelt J, Bochkarev A, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171462 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ral guanine nucleotide dissociation stimulator Chains: A, B
Molecule details ›
Chains: A, B
Length: 140 amino acids
Theoretical weight: 16.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q12967 (Residues: 793-914; Coverage: 13%)
Gene names: KIAA1308, RALGDS, RGF
Sequence domains: Ras association (RalGDS/AF-6) domain
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

1 bound ligand:
Ligand UNX 4 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P61
Unit cell:
a: 104.59Å b: 104.59Å c: 39.819Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.205 0.204 0.226
Expression system: Escherichia coli BL21

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