› 3kho

X-ray diffraction
3.11Å resolution

Crystal structure of murine Ig-beta (CD79b) homodimer

Released:
DOI: 10.2210/pdb3kho/pdb
PDB entry 3kho coloured by chain, front view.
PDB entry 3kho coloured by chain, side view.
PDB entry 3kho coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural and functional studies of Igalphabeta and its assembly with the B cell antigen receptor.
Radaev S, Zou Z, Tolar P, Nguyen K, Nguyen A, Krueger PD, Stutzman N, Pierce S, Sun PD
Structure 18 934-43 (2010)
PMID: 20696394

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147399 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
B-cell antigen receptor complex-associated protein beta chain Chains: A, B
Molecule details ›
Chains: A, B
Length: 133 amino acids
Theoretical weight: 15.08 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P15530 (Residues: 27-159; Coverage: 66%)
Gene names: Cd79b, Igb
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P41212
Unit cell:
a: 87.97Å b: 87.97Å c: 75.29Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.206 0.258
Expression system: Escherichia coli

Quick links

Citations

7 review citations

The tipping points in the initiation of B cell signalling: how small changes make big differences.
Pierce et al. (2010)
6 more