› 3kj7

X-ray diffraction
1.91Å resolution

Crystal Structure of the Complex of C-lobe of Bovine Lactoferrin with Dextrin at 1.9 A Resolution

Released:
DOI: 10.2210/pdb3kj7/pdb
PDB entry 3kj7 coloured by chain, front view.
PDB entry 3kj7 coloured by chain, side view.
PDB entry 3kj7 coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Specific interactions of C-terminal half (C-lobe) of lactoferrin protein with edible sugars: binding and structural studies with implications on diabetes.
Mir R, Kumar RP, Singh N, Vikram GP, Sinha M, Bhushan A, Kaur P, Srinivasan A, Sharma S, Singh TP
Int J Biol Macromol 47 50-9 (2010)
PMID: 20371371

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150260 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (4 distinct):
Lactotransferrin Chain: A
Molecule details ›
Chain: A
Length: 345 amino acids
Theoretical weight: 37.66 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P24627 (Residues: 361-705; Coverage: 50%)
Gene name: LTF
Sequence domains: Transferrin
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: GLC, BGC
Carbohydrate polymer
4 bound ligands:
Ligand SO4 1 x SO4
Ligand ZN 2 x ZN
Ligand FE 1 x FE
Ligand CO3 1 x CO3
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P21
Unit cell:
a: 61.81Å b: 50.134Å c: 65.545Å
α: 90° β: 107.1° γ: 90°
R-values:
R R work R free
0.211 0.209 0.241

Quick links

Citations

1 review citation

To Boost or to Reset: The Role of Lactoferrin in Energy Metabolism.
Ianiro et al. (2023)
5 other articles