Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Superantigen, staphylococcal/streptococcal toxin, bacterial
- Anaphylatoxin, complement system domain
- Staphylococcus aureus exotoxin
- Netrin module, non-TIMP type
- Alpha-macroglobulin, receptor-binding
- Alpha-macroglobulin, receptor-binding domain superfamily
- Anaphylatoxin/fibulin
- Alpha-2-macroglobulin, bait region domain
14 more domains
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-102037 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Complement C5
Molecule details ›
Chains: A, B
Length: 1676 amino acids
Theoretical weight: 188.53 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 1676 amino acids
Theoretical weight: 188.53 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P01031 (Residues: 1-1676; Coverage: 100%)
Sequence domains:
- Macroglobulin domain MG1
- MG2 domain
- Macroglobulin domain MG3
- Macroglobulin domain MG4
- Alpha-2-macroglobulin bait region domain
- Anaphylotoxin-like domain
- Alpha-2-macroglobulin family
- A-macroglobulin TED domain
- Complement component 5, CUB domain
- A-macroglobulin receptor binding domain
- UNC-6/NTR/C345C module
Staphylococcal superantigen-like 7
Molecule details ›
Chains: X, Y
Length: 103 amino acids
Theoretical weight: 11.77 KDa
Source organism: Staphylococcus aureus subsp. aureus str. Newman
Expression system: Escherichia coli
UniProt:
Sequence domains: Staphylococcal/Streptococcal toxin, beta-grasp domain
Length: 103 amino acids
Theoretical weight: 11.77 KDa
Source organism: Staphylococcus aureus subsp. aureus str. Newman
Expression system: Escherichia coli
UniProt:
- Canonical: A0A0H3K6Z8 (Residues: 129-231; Coverage: 51%)
Sequence domains: Staphylococcal/Streptococcal toxin, beta-grasp domain
