› 3kqg

X-ray diffraction
2.3Å resolution

Trimeric Structure of Langerin

Released:
DOI: 10.2210/pdb3kqg/pdb
PDB entry 3kqg coloured by chain, front view.
PDB entry 3kqg coloured by chain, side view.
PDB entry 3kqg coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Trimeric structure of langerin.
Feinberg H, Powlesland AS, Taylor ME, Weis WI
J Biol Chem 285 13285-93 (2010)
PMID: 20181944

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193806 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-type lectin domain family 4 member K Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 182 amino acids
Theoretical weight: 20.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UJ71 (Residues: 147-328; Coverage: 56%)
Gene names: CD207, CLEC4K
Sequence domains: Lectin C-type domain
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand CA 6 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P21
Unit cell:
a: 80.78Å b: 77.46Å c: 85.92Å
α: 90° β: 94.42° γ: 90°
R-values:
R R work R free
0.185 0.182 0.238
Expression system: Escherichia coli

Quick links

Citations

5 review citations

An evolutionary perspective on C-type lectins in infection and immunity.
van den Berg et al. (2012)
4 more

12 mentions without citation

Molecular Recognition in C-Type Lectins: The Cases of DC-SIGN, Langerin, MGL, and L-Sectin.
Valverde et al. (2020)
11 more