› 3kur

X-ray diffraction
2.5Å resolution

Crystal structure of the MLLE domain of poly(A)-binding protein

Released:
DOI: 10.2210/pdb3kur/pdb
PDB entry 3kur coloured by chain, front view.
PDB entry 3kur coloured by chain, side view.
PDB entry 3kur coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Molecular determinants of PAM2 recognition by the MLLE domain of poly(A)-binding protein.
Kozlov G, Ménade M, Rosenauer A, Nguyen L, Gehring K
J Mol Biol 397 397-407 (2010)
PMID: 20096703

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145989 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Polyadenylate-binding protein 1 Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 79 amino acids
Theoretical weight: 8.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P11940 (Residues: 544-617; Coverage: 12%)
Gene names: PAB1, PABP, PABP1, PABPC1, PABPC2
Sequence domains: Poly-adenylate binding protein, unique domain
Structure domains: c-terminal domain of poly(a) binding protein

Ligands and Environments

1 bound ligand:
Ligand CL 5 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F2
Spacegroup: P43212
Unit cell:
a: 146.977Å b: 146.977Å c: 83.055Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.218 0.216 0.272
Expression system: Escherichia coli

Quick links

Citations

12 review citations

Fungal development of the plant pathogen Ustilago maydis.
Vollmeister et al. (2012)
11 more

1 mention without citation

Crystal Structure of a Variant PAM2 Motif of LARP4B Bound to the MLLE Domain of PABPC1.
Grimm et al. (2020)