› 3ky9

X-ray diffraction
2.73Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147389 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Proto-oncogene vav Chains: A, B
Molecule details ›
Chains: A, B
Length: 587 amino acids
Theoretical weight: 68.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P15498 (Residues: 2-584; Coverage: 69%)
Gene names: VAV, VAV1
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand ZN 4 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 85.376Å b: 58.738Å c: 160.721Å
α: 90° β: 97.31° γ: 90°
R-values:
R R work R free
0.225 0.223 0.27
Expression system: Escherichia coli

Quick links

Citations

27 review citations

Intrinsically disordered proteins in cellular signalling and regulation.
Wright et al. (2015)
26 more

14 mentions without citation

How Bacteria Subvert Animal Cell Structure and Function.
Jimenez et al. (2016)
13 more